“New York, Detroit and Sicilian pies with scratch-made dough.”
Coast to Coast Pizza Company opened its Key Largo shop in 2025 at mile marker 99.6, its third location after Marathon and Fort Lauderdale. It's woman- and veteran-owned.
The pizza comes three ways, New York, Detroit and Sicilian, all with dough and sauces made from scratch. The key lime pie comes from their sister restaurant, SS Wreck on Grassy Key.
Coast to Coast Pizza Company is part of Taste the Keys for October 2026, the Key Largo Chamber of Commerce's month of prix-fixe menus at Upper Keys restaurants. Lunch is $18 and dinner is $26. Tax and tip are extra. The signature dish is the SS Wreck Key Lime Pie. The rest of the lineup is in our October in the Keys guide.
Address
99625 Overseas Hwy, Suite 1, Key Largo, FL 33037
Phone
(305) 204-4085Website
Visit WebsiteHours
Mon to Fri 11 am to 9 pm (call for weekend hours)
Mile Marker
99.6
Best For
Pizza night, takeout for the boat, and key lime pie.
106 Oceanside“Dock-and-dine on the Manatee Canal in Garden Cove.”
99.5 Bayside“A sunset bar on Florida Bay at mile marker 99.5.”
106.5 Oceanside“A seafood place on the water, tucked one block off US 1.”
